Difference between Latin American and Spain Spanish?

Hey everyone.

I’m trying to get into learning Spanish and have come to a bit of a crossroads. For many products for language learning, there’s two forms of Spanish. Latin American and Spain. What exactly are the differences? Like Rosetta Stone for instance. I can get Latin American, or Spain.

Is the difference just with pronunciation? If I were to learn Latin American Spanish, would I be able to go speak and read in Spain without any problems? I’m more interested in Spain, but I’m really curious as to what the differences are and if the differences are big enough to cause problems?

Thanks in advance!
OK, so ‘you’ is different. Is that all?